IPAP 2018

IPAP: the first World Congress of Faculties of Pharmacy: Innovations in Pharmacy Advances and Perpectives (Congress website), held in Salamanca, Spain, on September 24th-28th, 2018, on the occasion of the 8th Centenary of the foundation of the University of Salamanca. TRECARD Toxicology Team presented the communication entitled: “How to develop a mooc step by step in the context of higher education. The TOX-OER project experience”.

Cristina Cuesta Apausa obtained her PhD degree:

PhD student Cristina Cuesta Apausa obtained her doctorate on September 27th, 2018, with her thesis entitled “Urinary biomarkers for the identification of subclinical sequelae of acute kidney injury and recovery”, and obtained the maximal honours. The evaluation committee consisted of Prof. Dr. Nélida Eleno Balboa (President), University of Salamanca, Dr. Jose Manuel Muñoz Félix (Secretary), Queen Mary University of London, and Prof. Dr. Marta Ruiz Ortega (Member), from the Autonoma University of Madrid.

Tesis IMG_1620

ALCER Workshop

On the occasion of World Transplantation Day (6th, June), TRECARD Toxicology Unit has presented to ALCER association (Association of Renal Patients), the TOX-OER MOOC, in order to facilitate the inclusion of people with renal damage to patient education programs. TOX-OER is a free useful tool for them to learn what their disease is, the possible complications and treatments.

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55th ERA-EDTA Congress

Dr. Francisco J. López Hernández and Dr. Carlos Martínez Salgado presenting his recent findings at the 55th ERA-EDTA Congress held in Copenhaguen, Denmark, May 24th-27th, 2018.

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Opposition Competition

On May 3rd, two opposition competitions for access to university teaching bodies were held. The appointed Qualifying Commission awarded the position of Profesor Contratado Doctor to Dra. M. Prieto and Dr. M. Pescador for being the candidates that obtained the highest score.


Front line (right to left) Dr. M. Pescador and Dr. M. Prieto, in the background the members of the Qualifying Commission.

BIOCRITIC 2018. Curso Innovación y vanguardia en medicina crítica

TRECARD participates in “BIOCRITIC 2018. Curso Innovación y vanguardia en medicina crítica” with the lecture “Differential pathophysiology and conceptual perspectives for the differentiation and diagnosis of the forms of acute renal damage”. The course was held in Valladolid on March 15-16, 2018.

Biocritic 2018

Alfredo G. Casanova obtained his PhD degree

PhD student Alfredo G. Casanova obtained his doctorate on March 6th, 2018. He presented and defended his thesis entitled “Urinary biomarkers of kidney damage risk in the field of oncological therapy”, and obtained the maximal honours. The evaluation committee consisted of Prof. Dr. Jaime Feliu Batlle (President), Autonomous University of Madrid, Dr. Josep Gregori Font (Secretary) Roche Diagnostics S.L. Barcelona, and Prof. Dr. Fernando Manuel Gomes Remiao (Member), from the University of Porto.


TRECARD received the Prize of the Academy of Pharmacy of Castilla y León, with the work presented with the title “CARDIOTROFIN-1 REDUCES RENAL FIBROSIS IN MICE: THERAPEUTIC USE IN PREVENTION OF CHRONIC RENAL DISEASE”, whose authors are: Carlos Martínez Salgado,  Nuria Perretta-Tejedor, José M. Muñoz-Félix, Isabel Fuentes-Calvo, and Francisco J. López-Hernandez.

Notification of awards

In accordance with the rules of the call for prizes, Carlos Martinez Salgado was appointed Corresponding Academician of this Academy.

Victor Blanco obtained his PhD degree

PhD student Victor Blanco obtained his PhD degree last December 20th, 2017. He presented and defended his thesis titled “Etiopathogenic characterization of different experimental models of acute kidney injury: Biomarkers, pathophysiological mechanisms and clinical diagnosis applications”, and obtained maximal honours. The judging commission was formed by Prof. Dr. Ana I. Morales (Chair), from the University of Salamanca, Prof. Dr. Juan A. Moreno (Secretary), from the Universidad Autónoma de Madrid, and Prof. Dr. E. Tamayo (Member), from the University of Valladolid.

TRECARD attends the Young Nephrologists Programme Course – Acute Kidney Injury

The course was sponsored by the European Renal Association-European Dialysis & Transplantation Association (ERA-EDTA).



EUSTM-2017 – Annual Congress of the European Society of Translational Medicine

TRECARD participated in the 5th Annual European Conference on Clinical and Translational Sciences (EUSTM-2017), held in Berlin (October 20-22, 2017), with two lectures and one poster presentation. Carlos Martínez-Salgado spoke on “Normalization of renal function after AKI: is it a real reflection of a healthy renal state?”, Francisco J. López-Hernández on “Multi-technological development of a clinical decision support system for acute kidney injury prevention in the context of hypertension and pain treatment”, and Ana I. Morales presented “Utility of new biomarkers to identify the risk of developing AKI in patients treated with cisplatin”



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2nd Disease Maps Community Meeting

As a member of the consortium, TRECARD attended the 2nd Disease Maps Community Meeting. Francisco Lopez-Hernandez lectured on “The regulatory network of systemic and renal hemodynamics: the basis for the AKIPREV project”.

Link to the page

Disease Map


TRECARD participated in URINOMICS 2017, a congress on nephrology and omics held in Caparica (Portugal), September 18-21, 2017, which was organized by the BioScope Group & Proteo Mass Scientific Society. Francisco López gave a talk on “AKIPREV: A project to develop an innovative clinical decision support system to stratify patients and personalize antihypertensive and analgesic drug therapies, focused on the prevention of acute kidney injury”.

Doctoral Thesis Defence

On July 26th, 2017, Laura Prieto-García presented and defended her Doctoral Thesis titled “Pathophysiological characterization of an experimental model for triple whammy acute kidney injury: Differential and preventive diagnosis”. The Commission scored it with the maximal calification.

Doctoral Thesis Defence

Mrs. Nuria Perreta Tejedor, Pharmacist and researcher at TRECARD, presented her doctoral thesis titled: “Protective effect of cardiotrophin-1 in tubulointerstitial fibrosis and glomerulonephritis” on July 14, 2017, obtaining the highest rating.

tesis nuria

XXII Spanish Congress of Toxicology and VI Iberoamerican (XXII Congreso Español de Toxicología y VI Iberoamericano)

TRECARD researchers belonging to the Toxicology unit have participated in the XXII Spanish Congress of Toxicology and VI Iberoamerican (Valencia, Spain. June 28th-30th, 2017), with 2 oral comunications and 4 poster.

Alfredo G. Casanova, María T. Hernández-Sánchez and Laura Vicente-Vicente in Toxicology Congress in Valencia.

VII Course of Advances in Clinical Nephrology

Francisco J. López Hernández (TRECARD) lectures at the VII Course of Advances in Clinical Nephrology, organized by the University Hospital Fundación Jiménez Díaz (Madrid, June 12th, 2017) on “New pathogenic mechanisms of acute kidney injury. New biomarkers, new therapies”.

VII Curso Avances en Nefrología Clínica

ALCER Popular Race

TRECARD collaborated with ALCER (National Federation of Associations for the Fight against Kidney Diseases) in their yearly popular race in Salamanca (June 11th, 2017). Members of TRECARD participated in the race and in the awards ceremony.

54th ERA-EDTA Congress

TRECARD participated in the 54th ERA-EDTA Congress in Madrid (June 3rd-6th, 2017) and contributed 16 poster presentations, 1 plenary talk and 2 session chairings.

Course “Effect of Toxic in the Kidney” on the platform MiriadaX

Researchers from TRECARD belonging to the Toxicology Unit have developed the course “Effect of Toxic in the Kidney” (in spanish) available on the MiriadaX platform. This course will be open from the 6th of June to the 10th of July 2017.

You can obtain more information about the same as well as make the free registration in the following link:


Scientific Coffee on “Cafe Alcaraván”

Carlos Martínez Salgado and Francisco J. López Hernández talked about ‘Diabetes, hypertension and renal disease in Salamanca’ at the Scientific Coffee on “Cafe Alcaraván” on April 19th, 2017.

Press Notes




TRECARD received third prize in the 2016 University-Industry Challenge Contest, awarded by the Castilla y Leon Regional Government Department of Education. The awards ceremony took place in Valladolid on April 5th, 2017.

Trecard empresa

Activities in the Worl Kidney Day 2017

TRECARD was invited of ALCER (Spanish Association of Renal Patients) to participate in the press conference convened annually on World Kidney Day, which this year focuses on “Obesity and Kidney Damage” (Salamanca, March 9th, 2017).

TRECARD recibe la invitación de ALCER (Asociación Española de Enfermos Renales) a participar en la rueda de prensa convocada anualmente en el Día Mundial del Riñón que este año versa sobre el tema “Obesidad y Daño Renal” (Salamanca, 9 marzo 2017).

Press Chronicles (Spanish)

El Norte de Castilla

Tribuna Salamanca

Crónica de Salamanca

Salud a Diario

Salamanca RTV al día

Press release published an article on TRECARD group (in Spanish).

link to the page

AKIPREV Meeting in Lyon, France

Carlos Martínez Salgado and Francisco J. López Hernández at the scientific meeting of the AKIPREV European project held in the European Institute for Systems Biology and Medicine (EISBM) in Lyon, France, on March 1st-2nd, 2017.

Lyon 2017.03.01 Lyon

From left to right: Bertrand De Meulder, Alexander Mazein, Maria Manuela Nogueira, Carlos Martínez Salgado, Charles Auffray, Christian Delles and Francisco J. López Hernández

Press Chronicles (in Spanish)

Media links reporting the discovery by TRECARD researchers of genetic polymorphisms involved in the cardiovascular risk associated with hypertension and diabetes.

La Gaceta de Salamanca

Salamanca 24 Horas

Cadena SER

Diario de Valladolid

Zamora 24 Horas

Dissemination and presentation of TOX-OER in opening conference

TOXOER Multiplier event, held in Salamanca on December 16th 2016. TOXOER (Learning Toxicology through Open Educational Resources) is a project which aims to design and develop an international Massive Open Online Course (MOOC) on Toxicology.

XXXVIII Congress of the Spanish Society of Physiological Sciences (SECF)

Cristina Cuesta-Apausa and Nuria Perreta-Tejedor present their recent research in the XXXVIII Congress of the Spanish Society of Physiological Sciences (SECF), held in Zaragoza, Spain, September 13rd-16th, 2016.

Pechakucha Night

Drs. Francisco J. Lopez Hernandez and Carlos Martinez Salgado presented the TRECARD research group in the 12th edition of Pechakucha Night in Salamanca, Spain, in May 5th, 2016 (video in spanish).

DISMOD platform kick-off meeting


DISMOD platform kick-off meeting held in Madrid in March 8th, 2016.

From left to right: Hesham S. Abdallah, Jan Kubalik, Manon van Leeuwen, Victor Blanco, Miguel Pericacho, Ana I. Morales, Laura Prieto, Armin Kurtz, Bertram de Moulder, Alberto Ortiz, Patrick D´Haese, Francisco J. López, Carlos Martínez and José D. Martín.

TRECARD Association

On November 25th, 2015, the Translational Research on Renal and Cardiovascular Diseases Association (TRECARD Association) was born in order to raise and manage funds from different sources (grants, donation, crowfunding) for the development of their scientific activities.

3rd Congress of the European Society for Translational Medicine (EUSTM) held in Vienna, Austria, September 1st-4th, 2015

Inteview with Dr. Carlos Martínez Salgado in the 3rd Congress of the European Society for Translational Medicine (EUSTM), held in Vienna, Austria, September 1st-4th, 2015


Dr. Francisco J. López Hernández presenting his recent findings at the 3rd Congress of the European Society for Translational Medicine (EUSTM) held in Vienna, Austria, September 1st-4th, 2015


Dr. Carlos Martínez Salgado presenting his recent findings at the 3rd Congress of the European Society for Translational Medicine (EUSTM) held in Vienna, Austria, September 1st-4th, 2015.

2nd Congress of the European Society for Translational Medicine (EUSTM) congress held in Vienna, Austria, September 22nd-25th, 2014


Dr. Carlos Martínez Salgado presenting his lecture at the 2nd Congress of the European Society for Translational Medicine (EUSTM) congress held in Vienna, Austria, September 22nd-25th, 2014.


Members of the Global Translational Medicine Consortium (GTMC), from the European Society for Translational Medicine (EUSTM): Dr. Ana I. Morales Martín (2nd from the right), Dr. Francisco J. López Hernández (3rd from the right) and Dr. Carlos Martínez Salgado (4th from the right) in Vienna, Austria, September 25th 2014.

An international initiative to develop an innovative computerized diagnostic system for the prognostic monitoring of systemic and renal hemodynamics and prevention of pre-renal acute kidney injury.

Pathophysiology, pharmacokinetics, pharmacogenomics, systems medicine, mathematical modelling and software engineering.

Drugs, medical and diagnostic procedures may substantially alter systemic and renal hemodynamics leading to pre-renal acute kidney injury (AKI) and other syndromes, including cerebral hypoperfusion. Co-morbidities and predisposing factors, including environmental and genetic factors, determine the hemodynamic effect of drugs and procedures, as they set the pathophysiological grounds on which all these factors act. In order to gain a holistic view of hemodynamics, more complete pathophysiological knowledge on many different circumstances combining factors potentially altering systemic and renal hemodynamics, BP, volemia, RBF and GFR must be gained from empirical experimentation. This knowledge, along with pharmacokinetic profiling, and genetic and pharmacogenetic knowledge on inter-individual differences in drug handling, distribution, elimination and metabolism must be integrated through a systems medicine approach with the molecular signalling networks involved. Integrated knowledge should then form the basis of a mathematical modelling system coupled to friendly software interfaces that allow professionals to monitor the patient’s hemodynamic profile in a personalized manner; and to prevent undesired outcomes by predictive forecasts provided by the model when challenged with additional factors or manoeuvers. . We intend to lead a consortium and a H2020 proposal to fully develop a first operating version of this integrative diagnostic system. For this purpose, partnering and cooperation is sought from industrial and academic entities with different pre-clinical, clinical and technological capabilities.